Can you really deposit your data in a public repository?
Description
Sometimes it is difficult to determine if publishing data you have at hand is the right thing to do. Some reasons for hesitations might be that you have not used the data in a publication yet and don’t want to be scooped, that the data contains personal information about patients or that the data was collected or produced in a collaboration.
Considerations
- Publishing data does not necessarily mean open access nor public. Data can be published with closed or restricted access.
- Data doesn’t have to be published immediately while you are still working on the project. Data can be made available during the revision of the paper or after the publication of the paper.
- Make sure to have the rights or permissions to publish the data.
- Is the data commercially-sensitive?
- Does the data contain confidential/restricted information?
- Who controls the data?
Solutions
- If ethical, legal or contractual issues apply to your data type (e.g. personal or sensitive data, confidential or third-party data, data with copyright, data with potential economic or commercial value, intellectual property or IP data, etc.), ask for help and advice from the Legal Team, Tech Transfer Office, and/or Data Protection Officer of your institute.
- Decide what is the right type of access for your data, for instance:
- Open access.
- Registered access or with authentication procedure.
- Controlled access or via Data Access Committees (DACs).
- Decide what licence should be applied to your metadata and data.
- Certain repositories offer solutions for depositing data that need to be under restricted access. This allows for data to be findable even when it can not be published openly. One example is the The European Genome-phenome Archive (EGA) that can be used to deposit potentially identifiable genetic and phenotypic human data.
- Many repositories provide the option to put an embargo on a deposited dataset. This might be useful if you prefer to use the data in a publication before making it available for others to use.
- Establish an agreement outlining the controllership of the data and each collaborators’ rights and responsibilities.
- Even if the data cannot be published, it is good practice to publish the metadata of your datasets.
Which repository should you use to publish your data?
Description
Once you have completed your experiments and have performed quality control of your data it is good scientific practice to share your data in a public repository. Publishing your data is often required by funders and publishers.
The most suitable repository will depend on the data type and your discipline.
Considerations
- What type of data are you planning to publish?
- Does the repository need to provide solutions for restricted access for sensitive data?
- Do you have the rights to publish the data via the repository?
- How sustainable is the repository, will the data remain public over time?
- How FAIR is the repository?
- Does the funding agency or the scientific journal pose specific requirements regarding data sharing?
- What are the repository’s policies concerning licences and data reuse?
Solutions
- Based on the possible ethical, legal and contractual implications of your data, decides:
- The right type of access for your data.
- The licence that should be applied to your metadata and data.
- Check if/what discipline-specific repositories can apply the necessary access conditions and licences to your (meta)data.
- Discipline-specific repositories: if a discipline-specific repository, recognised by the community, exists this should be your first choice since discipline-specific repositories often increases the FAIRness of the data.
- The EMBL-EBI’s data submission wizard can help you choose a suitable repository based on your data type.
- There are lists of discipline-specific, community-recognised repositories e.g.:
- ELIXIR Deposition Databases for Biomolecular Data including ArrayExpress, BioModels, BioStudies, European Nucleotide Archive (ENA), PDB, PRIDE
- Scientific Data journal’s recommended repositories
- Wellcome Open Research - Data Guidelines
- Check if there are repositories available for specific data formats, such as images (e.g. BioImageArchive, EMPIAR) or earth and environmental science data (e.g. PANGAEA).
- General-purpose and institutional repositories: For other cases, a repository that accepts data of different types and disciplines should be considered. It could be a general-purpose repository, such as Zenodo, Mendeley data, FigShare, Dryad or a centralised repository provided by your institution or university.
- re3data or Repository Finder gather information about existing repositories and allows you to filter them based on access and licence types.
- re3data and FAIRsharing websites gather features of repositories, which you can filter by discipline, data type, taxonomy and many other features.
How do you prepare your data for publication in data repositories?
Description
Once you have decided where to publish your data, you will have to make your (meta)data ready for repository submission. For this reason it is recommended to become aware of repository’s requirements before start collecting the data.
Considerations
- What file formats should be used for the data?
- How is the data uploaded?
- What metadata do you need to provide?
- Under which licence should the data be published?
- Should sensitive data and metadata be anonymised or pseudonymised prior to a publication? This could notably be the case if you work with human data.
- After data is submitted to a public repository, should the original copy of the data be retained at the central brokering platform and linked to its public counterpart? Or should it be removed and replaced with the ID of the public record?
Solutions
- Learn the following information about the chosen repositories:
- Required metadata schemas
- Required ontologies or controlled vocabularies
- Accepted file formats for data and metadata
- Costs for sharing and storing data
- Repositories generally have information about data formats, metadata requirements and how data can be uploaded under a section called “submit”, “submit data”, “for submitters” or something similar. Read this section in detail.
- To ascertain re-usability data should be released with a clear and accessible data usage licence. We suggest making your data available under licences that permit free reuse of data, e.g. a Creative Commons licence, such as CC0 or CC-BY.
- Note that every repository can have one default licence for all datasets. For instance, sequence data submitted to for example European Nucleotide Archive (ENA) are implicitly free to reuse by others as specified in the International Nucleotide Sequence Database Collaboration (INSDC).
- See the corresponding pages for more detailed information about metadata, licences and data transfer.
- There are many tools available to remove human reads from your non-human data, e.g. Metagen-FastQC
How do you update or delete a published entry from a data repository?
Description
You will sometimes need to update or delete some entries that were incomplete or wrongly submitted for publication. Note however that upon creation of a new record, data is generally tagged for distribution and selected metadata fields may be exchanged with other repositories. Thus, redistribution of updated records may not be triggered automatically and updating records fully can be a time consuming and manual process for the repository. Also, in general, submitted data may not be deleted, but may be suppressed from public view upon request. In a nutshell, it is therefore safer to make sure to submit the right entry from the start, rather than updating it or asking for its withdrawal at a later stage.
Considerations
- Does the repository offer the possibility to update a submission? For the data submitter, is this a manual procedure (e.g. email, web interface) or is it available through an Application Programming Interface (API) or Command Line Interface (CLI)?
- Does the repository offer the possibility to delete (or hide) submissions?
- Does the repository have a test-server where data can be submitted for testing purpose?
Solutions
Solutions are very much repository-dependent. For example, on the European Nucleotide Archive (ENA), entries can be easily updated using a CLI. However, the updated information is not automatically redistributed to other registries linked to ENA. Upon email request, entries may also be suppressed from public view. Note that ENA also has a test server to make test submissions before submitting to the actual production server, which can be very useful when sending large batches of data to test for any systematic errors. Please check these points with your repository of choice.
More information
Links to FAIR Cookbook
FAIR Cookbook is an online, open and live resource for the Life Sciences with recipes that help you to make and keep data Findable, Accessible, Interoperable and Reusable; in one word FAIR.
Tools and resources on this page
Tool or resource | Description | Related pages | Registry |
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ArrayExpress | A collection in BioStudies for archiving and publishing data from high-throughput functional genomics experiments. | Microbial biotechnology Single-cell sequencing | Tool info Standards/Databases Training |
BioImageArchive | The BioImage Archive stores and distributes biological images that are useful to life-science researchers. | Bioimaging data | Standards/Databases |
BioModels | A repository of mathematical models for application in biological sciences | Microbial biotechnology | Tool info Standards/Databases Training |
BioStudies | A database hosting datasets from biological studies. Useful for storing or accessing life sciences data without community-accepted repositories, and for linking components of data from multi-omics studies. | Microbial biotechnology Plant sciences Single-cell sequencing Project data managemen... | Tool info Standards/Databases Training |
Dryad | Open-source, community-led data curation, publishing, and preservation platform for CC0 publicly available research data | Bioimaging data Biomolecular simulatio... | Standards/Databases |
ELIXIR Deposition Databases for Biomolecular Data | List of discipline-specific deposition databases recommended by ELIXIR. | CSC IFB Marine Metagenomics NeLS Data discoverability Documentation and meta... | Standards/Databases |
EMBL-EBI's data submission wizard | EMBL-EBI's wizard for finding the right EMBL-EBI repository for your data. | ||
EMPIAR | Electron Microscopy Public Image Archive is a public resource for raw, 2D electron microscopy images. You can browse, upload and download the raw images used to build a 3D structure | OMERO Bioimaging data Structural Bioinformatics | Tool info Standards/Databases Training |
European Nucleotide Archive (ENA) | A record of sequence information scaling from raw sequcning reads to assemblies and functional annotation | Galaxy Plant Genomics Human pathogen genomics Microbial biotechnology Single-cell sequencing Data brokering Project data managemen... | Tool info Standards/Databases Training |
FAIRsharing | A curated, informative and educational resource on data and metadata standards, inter-related to databases and data policies. | FAIRtracks Health data Microbial biotechnology Plant sciences Data discoverability Data provenance Existing data Machine actionability Documentation and meta... | Standards/Databases Training |
FigShare | Data publishing platform
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Biomolecular simulatio... Identifiers Documentation and meta... | Standards/Databases Training |
International Nucleotide Sequence Database Collaboration | The International Nucleotide Sequence Database Collaboration (INSDC) is a long-standing foundational initiative that operates between DDBJ, EMBL-EBI and NCBI. INSDC covers the spectrum of data raw reads, through alignments and assemblies to functional annotation, enriched with contextual information relating to samples and experimental configurations. | Galaxy Microbial biotechnology Plant sciences | |
International Nucleotide Sequence Database Collaboration (INSDC) | A collaborative database of genetic sequence datasets from DDBJ, EMBL-EBI and NCBI | Galaxy Microbial biotechnology Plant sciences | Tool info |
Mendeley data | Multidisciplinary, free-to-use open repository specialized for research data | Biomolecular simulatio... Existing data | Standards/Databases |
Metagen-FastQC | Cleans metagenomic reads to remove adapters, low-quality bases and host (e.g. human) contamination | ||
PANGAEA | Data Publisher for Earth and Environmental Science | Tool info Standards/Databases Training | |
PDB | The Protein Data Bank (PDB) | Galaxy Intrinsically disorder... Structural Bioinformatics | Tool info Training |
PRIDE | PRoteomics IDEntifications (PRIDE) Archive database | Proteomics | Tool info Standards/Databases Training |
re3data | Registry of Research Data Repositories | Data discoverability Existing data Licensing | Training |
Repository Finder | Repository Finder can help you find an appropriate repository to deposit your research data. The tool is hosted by DataCite and queries the re3data registry of research data repositories. | ||
The European Genome-phenome Archive (EGA) | EGA is a service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects
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CSC TSD Human data | Tool info Standards/Databases Training |
Wellcome Open Research - Data Guidelines | Wellcome Open Research requires that the source data underlying the results are made available as soon as an article is published. This page provides information about data you need to include, where your data can be stored, and how your data should be presented. | Standards/Databases | |
Zenodo | Generalist research data repository built and developed by OpenAIRE and CERN | FAIRtracks Plant Phenomics Bioimaging data Biomolecular simulatio... Plant sciences Single-cell sequencing Identifiers | Standards/Databases Training |
National resources
Tools and resources tailored to users in different countries.
Tool or resource | Description | Related pages | Registry |
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DORA | Digit Object Repository at the Libr4RI (4 ETH Domain Research Institutes, that are EAWAG, EMPA, PSI, WSL). |
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OLOS | OLOS is a Swiss-based data management portal, to help Swiss researchers safely manage, publish and preserve their data. |
Data storage | |
SWISSUbase | SWISSUbase is a national cross-disciplinary solution for Swiss universities and other research organizations in need of local institutional data repositories for their researchers. The platform relies on international archiving standards and processes to ensure that data are preserved and accessible in the long-term. |
Data storage | |
PUBLISSO | Open access publishing platform for life sciences. |
Researcher Data Steward | |
Fairdata.fi | With the Fairdata Services you can store, share and publish your research data with easy-to-use web tools. |
CSC Researcher Data Steward Data storage Existing data | |
Federated EGA Finland | FEGA allows you to store and share sensitive data in Finland in a way that fulfils all the requirements of the General Data Protection Regulation (GDPR).
The European Genome-phenome Archive (EGA)
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CSC Researcher Data Steward Data sensitivity Existing data Human data | |
Sensitive Data Services for Research | CSC Sensitive Data Services for Research are designed to support secure sensitive data management through web-user interfaces accessible from the user’s own computer. |
CSC Researcher Data Steward Data sensitivity Data analysis Data storage Human data | |
FAIR-Aware | Online tool which helps researchers and data managers assess how much they know about the requirements for making datasets findable, accessible, interoperable, and reusable (FAIR) before uploading them into a data repository. |
Researcher Data management plan Compliance monitoring ... | |
DataverseNO | DataverseNO is a national, generic repository for open research data. Various Norwegian research institutions have established partner agreements about using DataverseNO as institutional repositories for open research data.
DATAVERSE
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Federated EGA Norway node | Federated instance collects metadata of -omics data collections stored in national or regional archives and makes them available for search through the main EGA portal. With this solution, sensitive data will not physically leave the country, but will reside on TSD.
The European Genome-phenome Archive (EGA)
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Human data Data sensitivity Existing data TSD | |
Norwegian COVID-19 Data Portal | The Norwegian COVID-19 Data Portal aims to bundle the Norwegian research efforts and offers guidelines, tools, databases and services to support Norwegian COVID-19 researchers. |
Human data Data sensitivity Existing data COVID-19 Data Portal | |
usegalaxy.no | Galaxy is an open-source, web-based platform for data-intensive biomedical research. This instance of Galaxy is coupled with NeLS for easy data transfer.
Galaxy
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Data analysis Data sensitivity Existing data NeLS | |
Federated EGA Sweden node | Secure archiving and sharing of genetic and phenotypic data resulting from Swedish biomedical research projects.
The European Genome-phenome Archive (EGA)
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Human data Data sensitivity Existing data | |
NBIS Data Management Consultation | Free consultation service regarding data management questions in life science research. |
Data management plan Data sensitivity | |
SciLifeLab Data Repository (Figshare) | A repository for publishing any kind of research-related data, e.g. documents, figures, or presentations.
FigShare
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Existing data | |
Swedish Pathogens Portal | The Swedish Pathogens Portal provides information, guidelines, tools and services to support researchers to utilise Swedish and European infrastructures for data sharing. |
COVID-19 Data Portal Human data Data sensitivity Existing data |